病原生物学——王环宇

　　一、个人简介

　　王环宇，博士生导师，世界卫生组织乙脑地区参比实验室主任；中国疾病预防控制中心病毒病预防控制所病毒性脑炎室主任；传染病溯源预警与智能决策全国重点实验室PI。

　　中国疫苗行业协会乙脑防控分会主任委员；中国医疗保健国际交流促进会副主任委员。Zoonoese、病毒学报、中华实验和临床病毒学杂志、中国人兽共患病学报、中国疫苗和免疫、中国媒介生物学及控制杂志和中国预防医学杂志编委。

　　荣获四项省部级成果，包括省部级一等奖一项、二等奖两项、三等奖一项。埃博拉出血热疫情防控工作中被授予由7部委联合颁发的“埃博拉出血热疫情防控先进个人”荣誉称号。承担多项国家自然科学基金、重点专项和科技重大专项等课题。主编和副主编出版书籍各1部，共获得授权专利4项，发表学术论文230篇（SCI 100篇）。

　　二、主要研究方向

　　主要研究方向是以乙型脑炎、蜱传脑炎、西尼罗脑炎为主的病毒性脑炎和虫媒病毒及相关疾病的病原学、流行病学、免疫学、分子生物学、致病机理及相应的诊断等方面研究。

　　三、代表性论文、成果

　　1.Li, F., J. Li, J. Song, Q. Yin, K. Nie, S. Xu, Y. He, S. Fu, G. Liang, Q. Wei, and H. Wang. 2023. Novel Orthonairovirus Isolated from Ticks near China-North Korea Border. Emerg Infect Dis 29:1254-1257

　　2.Yang H, Wang X, Wang Z, Wang G, Fu S, Li F, Yang L, Yuan Y, Shen K, Wang H, Wang Z. 2023. Peripheral Nerve Injury Induced by Japanese Encephalitis Virus in C57BL/6 Mouse. J Virol:e165822.

　　3.Li F, Feng Y, Wang G, Zhang W, Fu S, Wang Z, Yin Q, Nie K, Yan J, Deng X, He Y, Liang L, Xu S, Wang Z, Liang G, Wang H. 2023. Tracing the spatiotemporal phylodynamics of Japanese encephalitis virus genotypeI throughout Asia and the western Pacific. PLoS Negl Trop Dis 17:e11192.

　　4.Su W, Jiang L, Lu W, Xie H, Cao Y, Di B, Li Y, Nie K, Wang H, Zhang Z, Xu S. 2022. A Serotype-Specific and Multiplex PCR Method for Whole-Genome Sequencing of Dengue Virus Directly from Clinical Samples. Microbiol Spectr:e121022.

　　5.Yao X, Yin Q, Hu D, Fu S, Zhang W, Nie K, Li F, Xu S, He Y, Liang G, Li X, Wang H. 2022. In Vitro Infection Dynamics of Wuxiang Virus in Different Cell Lines. Viruses 14.

　　6.Wang Q, Yin Q, Fu S, Cheng J, Xu X, Wang J, Wu B, Tian X, Li Y, Lu J, He Y, Li F, Nie K, Xu S, Lu X, Wang H, Wang B, Liang G. 2022. Isolation and Identification of Sandfly-Borne Viruses from Sandflies Collected  from June to August, 2019, in Yangquan County, China. Viruses 14.

　　7.Wu D, Chen X, Liu W, Fu S, Li F, Liang G, Yang G, Zheng H, Li J, Yin Z, Li Y, Wang H. 2021. Emergence of Japanese encephalitis among adults 40 years of age or older in northern China: Epidemiological and clinical characteristics. Transbound Emerg Dis. 6, (68):3415-3423

　　8.He X, Yin Q, Zhou L, Meng L, Hu W, Li F, Li Y, Han K, Zhang S, Fu S, Zhang X, Wang J, Xu S, Zhang Y, He Y, Dong M, Shen X, Zhang Z, Nie K, Liang G, Ma X, Wang H. 2021. Metagenomic sequencing reveals viral abundance and diversity in mosquitoes from the Shaanxi-Gansu-Ningxia region, China. PLoS Negl Trop Dis 15:e9381.

　　9.Zhang Y, Lei W, Wang Y, Sui H, Liu B, Li F, He Y, Li Z, Fu S, Wang L, Xu L, Mahe M, Gao Z, Mamutijiang T, Lv Z, Xiang N, Zhou L, Ni D, Liang G, Li Q, Wang H, Feng Z. 2021. Surveillance of West Nile virus infection in Kashgar Region, Xinjiang, China, 2013-2016. Sci Rep 11:14010.

　　10.Wang, G., H. Li, X. Yang, T. Guo, L. Wang, Z. Zhao, H. Sun, X. Hou, X. Ding, C. Dou, Q. Ma, X. Yang, Y. Wang, Z. Wang, L. Wang, J. Liu, Z. Wang, H. Wang, and P. Xie. 2020. Guillain-Barre Syndrome Associated with JEV Infection. N Engl J Med 383:1188-1190.