公共卫生
硕导
公共卫生——陆柔剑
来源: 发布时间:2024-09-14

一、个人简介
陆柔剑,女,汉族,硕士,主任技师。
2008年毕业于中国疾病预防控制中心公共卫生管理专业,获公共卫生硕士学位,现在中国疾病预防控制中心病毒病预防控制所应急技术中心工作。
主要从事冠状病毒和正痘病毒病原学、诊断学、流行病学和疫苗学研究。长期致力于冠状病毒及常见呼吸道病毒的病原监测检测,多次参与突发公共卫生应急事件处置工作,包括2015年广东MERS输入病例疫情和2022年重庆猴痘输入病例疫情等。主持和参与多项国家级科研项目;在国内外专业期刊发表论文60余篇,包括Lancet、NEMJ、MBio等;获国家科技进步二等奖,北京市科技进步一等奖,中华医学会科学技术三等奖,华夏医学科学技术三等奖,并获2项国家专利授权。
二、主要研究方向
冠状病毒及常见呼吸道病毒分子流行病学研究,病毒基因组特征、遗传变异、进化规律及致病性研究,病毒诊断方法研究等。
三、代表性论文、成果
1. Lu R, Zhao X, Li J, Niu P, Yang B, Wu H, Wang W, Song H, Huang B, Zhu N, Bi Y, Ma X, Zhan F, Wang L, Hu T, Zhou H, Hu Z, Zhou W, Zhao L, Chen J, Meng Y, Wang J, Lin Y, Yuan J, Xie Z, Ma J, Liu WJ, Wang D, Xu W, Holmes EC, Gao GF, Wu G, Chen W, Shi W, Tan W. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet, 2020 Feb 22, 395(10224):565-574
2. Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, Zhao X, Huang B, Shi W, Lu R, Niu P, Zhan F, Ma X, Wang D, Xu W, Wu G, Gao GF, Tan W. A Novel Coronavirus from Patients with Pneumonia in China, 2019. N Engl J Med. 2020 Feb 20;382(8):727-733.
3. Zhang X*, Li R*, Lu R*, Wu C, Liang Z, Zhang Z, Huang B, Yang Y, Qi Z, Zhang D, Zhai D, Wang Q, Tan W. Transition of D3c branch and novel recombination events contribute to the diversity of Coxsackievirus A6 in Beijing, China, from 2019 to 2023. Virus Evol. 2025 May 11;11(1):veaf036.
4. Li F*, Lu R*, Zhang Y, Shi P, Ao Y, Cao L, Zhang Y, Tan W, Shen J. Clinical and molecular epidemiology of enterovirus D68 from 2013 to 2020 in Shanghai. Sci Rep. 2024 Jan 25;14(1):2161.
5. Lu R, Zhao L, Huang B, Ye F, Wang W, Tan W. Real-time reverse transcription-polymerase chain reaction assay panel for the detection of severe acute respiratory syndrome coronavirus 2 and its variants. Chin Med J (Engl), 2021 Aug 16;134(17):2048-2053
6.Lu R, Niu P, Zhao L, Wang H, Wang W, Tan W. Sequencing the Complete Genome of COVID-19 Virus from Clinical Samples Using the Sanger Method. China CDC Weekly, 2020;2(25): 447-452
7. Niu P*, Lu R*, Zhao L, Wang H, Huang B, Ye F, Wang W, Tan W. Three Novel Real-Time RT-PCR Assays for Detection of COVID-19 Virus. China CDC Weekly, 2020;2(25):453-457
8.Zhao Y*, Lu R*, Shen J*, Xie Z, Liu G, Tan W. Comparison of viral and epidemiological profiles of hospitalized children with severe acute respiratory infection in Beijing and Shanghai, China. BMC Infectious Diseases, 2019, 19:729
9. Zhao Y, Shen J, Wu B, Liu G, Lu R#, Tan W#. Genotypic Diversity and Epidemiology of Human Rhinovirus Among Children With Severe Acute Respiratory Tract Infection in Shanghai, 2013-2015. Front Microbiol, 2018 Aug 7, 9:1836.
10. Wang Y*, Liu D*, Shi W*, Lu R*, Wang W, Zhao Y, Deng Y, Zhou W, Ren H, Wu J, Wang Y, Wu G, Gao GF, Tan W. Origin and Possible Genetic Recombination of the Middle East Respiratory Syndrome Coronavirus from the First Imported Case in China: Phylogenetics and Coalescence Analysis. mBio. 2015 Sep 8;6(5):e01280-15.
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